Advances in Diabetes and Metabolism(CEASE PUBLICATION) Vol. 1(3), pp. 51 - 56
DOI: 10.13189/adm.2013.010301
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Clinical Correlation of Metabolic Syndrome in Indian Type-2 Diabetics Patients with Their Socioeconomic Status under Different Age Group


Manoj Kumar Upadhyay *
Scientist C, Biotech Park Lucknow, India

ABSTRACT

The metabolic syndrome is a complex condition in which numerous aspects of normal metabolism are perturbed. The syndrome represents a cluster of the major risk factors for cardiovascular disease i.e. obesity, insulin resistance / hyperinsulinemia, impaired glucose tolerance / diabetes, dyslipidemia and hypertension. The syndrome is also described by a procoagulant state that is attributed, in part, to an elevation in circulating lipoprotein, fibrinogen and plasminogen activator inhibitor one levels. This in turn contributes to the metabolic abnormalities that lead to cardiovascular disease. Several hypothesis have been proposed for the etiology of the metabolic syndrome, and the potential role of insulin resistance, leptin resistance, and other disturbances as major contributing factors. Hyperinsulinemia and insulin resistance are predictors of type 2 diabetes and are key factors in the development of the metabolic syndrome. A survey was conducted to study the clinical correlation of metabolic syndrome in Indian type –2 diabetic patients with their socioeconomic status (high income group, middle income group & low income group) under different age group (upper age group, middle age group & low income group) in western Uttar Pradesh, India. Four hundred five type 2 diabetic patients aged 52 ±17 year including 215 (53.09%) males and 190 ( 46.91%) females were surveyed for this purpose. Of these hypertension & diabetics were simultaneously diagnosed in 196 (48.39%) & 152 (37.53%) patients. Family history of these patients showed the occurrence of diabetes , hypertension & concurrent hypertension with diabetes mellitus in about 59 (14.0%), 56 (13.8%) & 77 (19.1%) respectively. The frequencies of individual component of the metabolic syndrome were as follows: dyslipidemia - 68.4%, systemic hypertension – 54.3% , obesity – 42.5% microalbuminuria – 44.9% & hyperuracemia 58.3% . Ischemic heart disease (myocardial infarction) occurs in – 2.4%. Of these 405 diabetic studies, 278(68.2%) had metabolic syndrome victims occurs in the high income group & the low income group.

KEYWORDS
Clinical Correlation, Metabolic Syndrome, Type – 2 Diebtics, Socioeconomical Status

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Manoj Kumar Upadhyay , "Clinical Correlation of Metabolic Syndrome in Indian Type-2 Diabetics Patients with Their Socioeconomic Status under Different Age Group," Advances in Diabetes and Metabolism(CEASE PUBLICATION), Vol. 1, No. 3, pp. 51 - 56, 2013. DOI: 10.13189/adm.2013.010301.

(b). APA Format:
Manoj Kumar Upadhyay (2013). Clinical Correlation of Metabolic Syndrome in Indian Type-2 Diabetics Patients with Their Socioeconomic Status under Different Age Group. Advances in Diabetes and Metabolism(CEASE PUBLICATION), 1(3), 51 - 56. DOI: 10.13189/adm.2013.010301.