Advances in Zoology and Botany Vol. 8(2), pp. 45 - 51
DOI: 10.13189/azb.2020.080202
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Gut Microbial Diversity in Rotenone Induced and Transgenically Created PD (Parkinson Disease) Flies of Drosophila Melanogaster


Ali Hatami Dehnow , Mysore Siddaiah Krishna *
Drosophila Stock Centre, Department of Studies in Zoology, University of Mysore, India

ABSTRACT

In the present study of gut microbial diversity in control and experimental treated D. melanogaster flies showed that there were two species belong to Acetobacter species group namely Acetobacter pomorum and Acetobacter tropicalis and three species belong to Lactobacillus species namely Lactobacillus brevis, Lactobacillus fructivorans and Lactobacillus plantarum. Further analysis revealed that the relative abundance of each of the above microbial species varies in control and experimental flies. The density of lactobacillus species such as L. brevis, L. fructivorans and L. plantarum were found to be lowest in control and creatine supplemented flies. While these species were highest in rotenone induced and transgenically created PD flies. Further A. pomorum and A. tropicalis were found to be lowest abundance in control and creatine treated flies whereas they were found to be greater abundance in rotenone induced and transgenically created PD flies of D. melanogaster. Thus, these studies suggest that significant influence of host diet related changes in gut microbial density in Drosophila.

KEYWORDS
Parkinson's Disease, Microbiota, 16S rRNA, Pyro Sequencing, D.melanogaster Transgenic Flies

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Ali Hatami Dehnow , Mysore Siddaiah Krishna , "Gut Microbial Diversity in Rotenone Induced and Transgenically Created PD (Parkinson Disease) Flies of Drosophila Melanogaster," Advances in Zoology and Botany, Vol. 8, No. 2, pp. 45 - 51, 2020. DOI: 10.13189/azb.2020.080202.

(b). APA Format:
Ali Hatami Dehnow , Mysore Siddaiah Krishna (2020). Gut Microbial Diversity in Rotenone Induced and Transgenically Created PD (Parkinson Disease) Flies of Drosophila Melanogaster. Advances in Zoology and Botany, 8(2), 45 - 51. DOI: 10.13189/azb.2020.080202.