International Journal of Biochemistry and Biophysics Vol. 6(1), pp. 26 - 31
DOI: 10.13189/ijbb.2018.060103
Reprint (PDF) (324Kb)

Concentrations of Fat-soluble Vitamins of Trema guineensis Aqueous and Ethanolic Extracts and Rats Supplemented

Droucoula Guillaume Cyril ^1,*, Tra Bi Irié Otis ^1,2, Miezan Bile Aka Patrice ¹, Kouakou Sylvain Landry ³, Bla Kouakou Brice ¹, Yapi Houphouët Félix ^1
1 Laboratory of Biochemical Pharmacodynamics, UFR Biosciences, Félix Houphouët-Boigny University, Côte d'Ivoire
² Laboratory of SVT, Higher Teacher Training School of Abidjan, Côte d'Ivoire
³ Laboratory of Pharmacology, Clinical and Therapeutic Pharmacy, UFR Pharmaceutical and Biologic Sciences, Félix Houphouët-Boigny University, Côte d'Ivoire

ABSTRACT

This study was undertaken to determine vitamins A, D and E composition of aqueous and ethanolic extracts of Trema guineensis and effect of supplementation of these extracts on serum concentrations of these vitamins. Aqueous and ethanolic extracts of Trema guineensis were obtained by decoction and maceration of leaves powder, respectively. Then, they were administered to animals at doses of 100 and 200 mg/kg body weight against a control group treated with distilled water for two weeks. Composition of vitamins in extracts and serum concentrations of vitamins A, D and E were performed by HPLC. Results showed that Trema guineensis extracts contained high concentrations of vitamins A, D and E. Thus, vitamins A and D serum concentrations were weakly influenced while that of vitamin E increased strongly during administration of Trema guineensis extracts. This study therefore showed that extracts of Trema guineensis had vitamins A, D and E and a beneficial effect on serum concentrations of these vitamins.

KEYWORDS
Trema guineensis, Vitamins A, D and E, Côte d'Ivoire

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Droucoula Guillaume Cyril , Tra Bi Irié Otis , Miezan Bile Aka Patrice , Kouakou Sylvain Landry , Bla Kouakou Brice , Yapi Houphouët Félix , "Concentrations of Fat-soluble Vitamins of Trema guineensis Aqueous and Ethanolic Extracts and Rats Supplemented," International Journal of Biochemistry and Biophysics, Vol. 6, No. 1, pp. 26 - 31, 2018. DOI: 10.13189/ijbb.2018.060103.

(b). APA Format:
Droucoula Guillaume Cyril , Tra Bi Irié Otis , Miezan Bile Aka Patrice , Kouakou Sylvain Landry , Bla Kouakou Brice , Yapi Houphouët Félix (2018). Concentrations of Fat-soluble Vitamins of Trema guineensis Aqueous and Ethanolic Extracts and Rats Supplemented. International Journal of Biochemistry and Biophysics, 6(1), 26 - 31. DOI: 10.13189/ijbb.2018.060103.