Universal Journal of Public Health Vol. 5(6), pp. 320 - 329
DOI: 10.13189/ujph.2017.050606
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Comparison of Different Saturation Pulse Types in a Series of Saturation Transfer Difference NMR Experiment Based on Cox-1 Enzyme and Ibuprofen Interaction


Nil E. Binbay 1,*, Berrin Ziyadanoğulları 2
1 Department of Electronics, Vocational School, Dicle University, Turkey
2 Faculty of Science, Dicle University, Turkey

ABSTRACT

Here we report, comparison of two different saturation pulse types with different shapes, Gaussian pulse and Reburp pulse. Pulses are comparatively used in a series of STD-NMR experiments for determine which one is more effective for saturation and also saturation transfer for ibuprofen and COX1 mixture. Both pulses have been comparatively studied, and they are applied to identical samples in identical experimental conditions to see the difference. Also they are examined over different pulse parameters, like lengths and powers. Finally it is shown that, re-burp pulse gives more intensive STD-NMR signals than Gaussian pulse shape under same conditions and same samples. That means Reburp pulse shape causes more effective saturation than Gaussian pulse shape for COX enzyme and ibuprofen. Results are in accordance with literature.

KEYWORDS
STD-NMR, Cyclooxygenase Enzyme, Ibuprofen, Gaussian Pulse, Reburp Pulse

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Nil E. Binbay , Berrin Ziyadanoğulları , "Comparison of Different Saturation Pulse Types in a Series of Saturation Transfer Difference NMR Experiment Based on Cox-1 Enzyme and Ibuprofen Interaction," Universal Journal of Public Health, Vol. 5, No. 6, pp. 320 - 329, 2017. DOI: 10.13189/ujph.2017.050606.

(b). APA Format:
Nil E. Binbay , Berrin Ziyadanoğulları (2017). Comparison of Different Saturation Pulse Types in a Series of Saturation Transfer Difference NMR Experiment Based on Cox-1 Enzyme and Ibuprofen Interaction. Universal Journal of Public Health, 5(6), 320 - 329. DOI: 10.13189/ujph.2017.050606.