International Journal of Biochemistry and Biophysics Vol. 5(1), pp. 19 - 25
DOI: 10.13189/ijbb.2017.050103
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Study of the in vitro Antibacterial Activity of the Aqueous and Hydroethanolic Extracts from the Leaves of the Erythrococca anomala (Euphorbiaceae) on Six Bacterial Strains

Miezan Bilé Aka Patrice ¹, Koffi Allali Eugene ^2,*, BY Philemon ¹, Okpekon Aboua Timothée ³, Yapi Houphouët Felix ^1
1 Laboratory of Biochemical Pharmacodynamics, UFR Biosciences, Felix Houphouet Boigny University, Côte d'Ivoire
² Biochemistry and Microbiology Department, UFR Agroforestry, University of Jean Lorougnon Guede, Côte d'Ivoire
³ Laboratory of Organic Chemistry and Natural Substances, UFR Sciences of Structures of Matter and Technology, Felix Houphouet Boigny University, Côte d'Ivoire

ABSTRACT

The problems of resistance of pathogenic bacteria to the common antibiotics in hospitals and the high costs of the treatments of pathologies caused by those resistant bacteria have brought about innovation in the search for alternative treatments: plants. The purpose of this study is to assess the antibacterial activities of the aqueous and hydroethanilic extracts from the leaves of the Erythrococca anomala on the in vitro growth of six multiresistant bacterial strains: Pseudomonas aeruginosa, Escherichia coli Klebsiella pneumoniae, Neisseria meningitidis, Streptococcus pneumoniae, Staphylococcus aureus, isolated from patients. The results of the studies showed that the aqueous extract, more active than the hydroethanolic extract, contains Minimal Inhibitory Concentrations (MICs) which vary between 0.78 mg/mL and 12.5 whereas the minimal bactericidal concentrations (MBCs) vary between 0.78 mg/mL and 25 mg/mL. Concerning the hydroethanolic extract, the MICs and the MBCs, vary between 3.125 mg/mL and 25 mg/mL each. Streptococcus pneumoniae and Staphylococcus aureus are more susceptible because they need 0.78 mg/mL and 1.56 mg/mL respectively before they are completely inhibited by the aqueous extract. Compared with the Ciprofloxacin, a pure molecule, those extracts have clearly better antibacterial activity. That may justify why those leaves are used in traditional areas as anti-infective treatment. Erythrocacca anomala is a glimmer of hope for the treatment of infectious diseases in Côte d'Ivoire.

KEYWORDS
Erythrococca anomala, Antibacterial Activity, In vitro

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Miezan Bilé Aka Patrice , Koffi Allali Eugene , BY Philemon , Okpekon Aboua Timothée , Yapi Houphouët Felix , "Study of the in vitro Antibacterial Activity of the Aqueous and Hydroethanolic Extracts from the Leaves of the Erythrococca anomala (Euphorbiaceae) on Six Bacterial Strains," International Journal of Biochemistry and Biophysics, Vol. 5, No. 1, pp. 19 - 25, 2017. DOI: 10.13189/ijbb.2017.050103.

(b). APA Format:
Miezan Bilé Aka Patrice , Koffi Allali Eugene , BY Philemon , Okpekon Aboua Timothée , Yapi Houphouët Felix (2017). Study of the in vitro Antibacterial Activity of the Aqueous and Hydroethanolic Extracts from the Leaves of the Erythrococca anomala (Euphorbiaceae) on Six Bacterial Strains. International Journal of Biochemistry and Biophysics, 5(1), 19 - 25. DOI: 10.13189/ijbb.2017.050103.