Journals Information
Universal Journal of Physics and Application Vol. 9(1), pp. 6 - 16
DOI: 10.13189/ujpa.2015.030102
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Reactive Centers of Curcumin and the Possible Role of Metal Complexes of Curcumin as Antioxidants
Priya. R. S 1, Balachandran. S 2, Joseph. Daisy 3,*, Mohanan. P. V 1
1 Department of Applied Chemistry, Cochin University of Science and Technology, India
2 Department of Chemistry, Mahatma Gandhi College, India
3 Nuclear Physics Division, Bhaba Atomic Research Center, India
ABSTRACT
Curcumin is known as a blood purifier in Ayurveda which has been recently ascribed to its chelating ability with metal, hence reducing the deposition of metal in the body. Curcumin can exhibit keto-enol tautomerism and in the synthesized 1:1 metal complexes, the enolate ion chelate to the metal. The antioxidant activity of the synthesized metal complexes of curcumin was slightly less than the parent curcumin-I. Curcumin in the complexed state retains its antioxidant behavior, consequently establishing importance of phenolic group in deciding its antioxidant activity. The study reveals that the flexibility at the diketo moiety is not a requisite for the radical formation and sufficient scavenging of DPPH occur by phenoxide ion formation.
KEYWORDS
Curcumin, Metal Complex, DPPH, Antioxidant
Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Priya. R. S , Balachandran. S , Joseph. Daisy , Mohanan. P. V , "Reactive Centers of Curcumin and the Possible Role of Metal Complexes of Curcumin as Antioxidants," Universal Journal of Physics and Application, Vol. 9, No. 1, pp. 6 - 16, 2015. DOI: 10.13189/ujpa.2015.030102.
(b). APA Format:
Priya. R. S , Balachandran. S , Joseph. Daisy , Mohanan. P. V (2015). Reactive Centers of Curcumin and the Possible Role of Metal Complexes of Curcumin as Antioxidants. Universal Journal of Physics and Application, 9(1), 6 - 16. DOI: 10.13189/ujpa.2015.030102.