Universal Journal of Public Health Vol. 12(4), pp. 650 - 659
DOI: 10.13189/ujph.2024.120404
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Factors Associated with Carbapenem-resistant Klebsiella pneumoniae Infections among Inpatients in a Tertiary Health Care Hospital

Wanwara Tonkulrat ¹, Wisit Chaveepojnkamjorn ^2,*, Peeraya Ekcjariyawat ³, Sirima Mongkolsomlit ^4
1 Nopparat Rajathanee Hospital, Thailand
² Department of Epidemiology, Faculty of Public Health, Mahidol University, Thailand
³ Department of Microbiology, Faculty of Public Health, Mahidol University, Thailand
⁴ Faculty of Public Health, Thammasat University, Thailand

ABSTRACT

Carbapenem-resistant Klebsiella pneumaoniae infections (CRKPIs) are major health problems of drug resistance worldwide. The present study aimed to determine factors associated with CRKPIs among inpatients in a tertiary healthcare hospital. A hospital-based case-control study was based on the medical records of the patients who were infected with K. pneumoniae after being admitted for more than 48 hours in the Nopparat Rajathanee Hospital (NRH) from January 1, 2020 to December 31, 2020. 145 patients with CRKPIs were assigned as cases while 290 patients with carbapenem-susceptible K. pneumoniae infections (CSKPIs) as controls. Descriptive statistics and multivariable logistic regression were used in data analysis. The average age of the study subjects was 69.3 years (SD = 15.6) among cases. The mean length of hospital stay among cases was 22.2 days (SD = 14.9). Multivariable logistic regression showed significant associations with CRKPIs, renal diseases (Adjusted OR = 2.1; 95%CI = 1.1-3.8), previous hospitalizations (Adjusted OR = 2.1; 95%CI = 1.2-3.8), central venous catheterization (CVC) > 7 days (Adjusted OR = 2.7; 95%CI = 1.1-6.8), and urinary catheter > 7 days (Adjusted OR = 2.7; 95%CI = 1.1-6.4). Therefore, it should be a guideline for surveillance of risk factors of CRKPIs among inpatients. Additionally, the results of the study can be used to monitor and assess the risk of CRKPIs to prevent the complications of patients.

KEYWORDS
Carbapenem-Resistant Klebsiella pneumoniae Infections, Inpatients, Tertiary Health Care Hospital

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Wanwara Tonkulrat , Wisit Chaveepojnkamjorn , Peeraya Ekcjariyawat , Sirima Mongkolsomlit , "Factors Associated with Carbapenem-resistant Klebsiella pneumoniae Infections among Inpatients in a Tertiary Health Care Hospital," Universal Journal of Public Health, Vol. 12, No. 4, pp. 650 - 659, 2024. DOI: 10.13189/ujph.2024.120404.

(b). APA Format:
Wanwara Tonkulrat , Wisit Chaveepojnkamjorn , Peeraya Ekcjariyawat , Sirima Mongkolsomlit (2024). Factors Associated with Carbapenem-resistant Klebsiella pneumoniae Infections among Inpatients in a Tertiary Health Care Hospital. Universal Journal of Public Health, 12(4), 650 - 659. DOI: 10.13189/ujph.2024.120404.