Advances in Zoology and Botany Vol. 11(5), pp. 367 - 374
DOI: 10.13189/azb.2023.110504
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Screening of Preliminary Phytochemicals and In vitro Antibacterial Activity of Methanolic Extracts of Stem, Leaf, Root and Leaf Callus of Corynandra felina (L.f.) Cochrane & Iltis

Medisetti Narendar ^1,*, Md Mustafa ², Pendli Sreenu ², Koppula Thirupathi ², Kusuma Shailaja ^1
1 Department of Botany, Osmania University, India
² Department of Botany, Kakatiya University, India

ABSTRACT

Corynandra felina (L.f.) Cochrane & Iltis, an endemic medicinal herb in peninsular India, belongs to the family Cleomaceae. It is used in traditional medicine for epistaxis, astringent, antihyperlipidemic, antidiabetic, anticancer, and anti-inflammatory therapies. This study was carried out to screen the preliminary phytochemicals in methanolic extracts of stem, leaf, root and leaf callus through chemical methods and reveal the presence of alkaloids, phenols, tannins, saponins, cardiac glycosides, terpenoids and anthraquinones. The methanolic extracts of stem, leaf, root and leaf callus show antibacterial activity against bacterial strains viz. Bacillus subtilis, Klebsiella pneumonia, Staphylococcus aureus, Pseudomonas fluorescens, Escherichia coli. Zone of inhibition values was used to evaluate the antibacterial activity. Maximum zone of inhibition 20.0 ± 0.2 mm was found in stem extract against Klebsiella pneumonia, 15.2± 0.2 mm was found in leaf extract against Klebsiella pneumonia and no activity was observed in root and leaf callus extracts. Our study revealed that the phytochemicals of C. felina are showing antimicrobial activity and there is a possibility to develop drugs against pathogenic bacterial strains.

KEYWORDS
Cleome felina, Endemic, Phytochemical, Antibacterial Activity, Zone of Inhibition, Klebsiella pneumonia

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Medisetti Narendar , Md Mustafa , Pendli Sreenu , Koppula Thirupathi , Kusuma Shailaja , "Screening of Preliminary Phytochemicals and In vitro Antibacterial Activity of Methanolic Extracts of Stem, Leaf, Root and Leaf Callus of Corynandra felina (L.f.) Cochrane & Iltis," Advances in Zoology and Botany, Vol. 11, No. 5, pp. 367 - 374, 2023. DOI: 10.13189/azb.2023.110504.

(b). APA Format:
Medisetti Narendar , Md Mustafa , Pendli Sreenu , Koppula Thirupathi , Kusuma Shailaja (2023). Screening of Preliminary Phytochemicals and In vitro Antibacterial Activity of Methanolic Extracts of Stem, Leaf, Root and Leaf Callus of Corynandra felina (L.f.) Cochrane & Iltis. Advances in Zoology and Botany, 11(5), 367 - 374. DOI: 10.13189/azb.2023.110504.