Universal Journal of Public Health Vol. 2(2), pp. 58 - 63
DOI: 10.13189/ujph.2014.020204
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Congenital Anomalies: Prevalence and Risk Factors


Rizk Francine 1, Salameh Pascale 2, Hamadé Aline1a 3,*
1 Department of Life and Earth Sciences, Faculty of Sciences, Branch II, Lebanese University, Beirut, Lebanon
2 Laboratory of Clinical and Epidemiological Research, Faculty of Pharmacy, Lebanese University, Beirut, Lebanon
3 Department of Biology, Faculty of Sciences II, Lebanese University, Fanar, Lebanon

ABSTRACT

Objective: The aim of this study is to assess the incidence, types and correlates of congenital anomalies (CA) among stillborn and liveborn infants in two Lebanese hospitals in Mount-Lebanon. Methods: In this cross-sectional study, all the newborns who were born during 9 months period from January to December 2009 (n=1000) at two hospitals setting in Mount-Lebanon hospital, Lebanon were studied. The newborns were assessed for CA. Neonatal data were extracted from medical records of the nursery. The classification of malformations was based upon the anatomical system affected according to the WHO classification of CA. Results: Of the all 1000 single births, 24 (2.4%) were diagnosed as being congenitally malformed. Cardiovascular system defects and limbs anomalies (4/1000) were mostly detected, followed by genitourinary system (2/1000), nervous system (2/1000), respiratory system (2/1000) malformations and chromosomal anomalies (1/1000). A marked association of parental consanguinity and alcohol consumption of the mother during the pregnancy with increased CA rates was found (p= 0.015 and p=0.027 respectively). Conclusions: The frequency of malformations in the study was approximately similar to previous investigations. The increased incidence of CA in cases of parental consanguinity prompts the necessity of establishing educational programs to avoid these complications in the offspring.

KEYWORDS
Newborn, Defects, Epidemiology, Consanguinity, Lebanon

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Rizk Francine , Salameh Pascale , Hamadé Aline1a , "Congenital Anomalies: Prevalence and Risk Factors," Universal Journal of Public Health, Vol. 2, No. 2, pp. 58 - 63, 2014. DOI: 10.13189/ujph.2014.020204.

(b). APA Format:
Rizk Francine , Salameh Pascale , Hamadé Aline1a (2014). Congenital Anomalies: Prevalence and Risk Factors. Universal Journal of Public Health, 2(2), 58 - 63. DOI: 10.13189/ujph.2014.020204.