Advances in Zoology and Botany Vol. 10(1), pp. 11 - 17
DOI: 10.13189/azb.2022.100102
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Cytotoxic and Antimicrobial Activity of Common Invasive Alien Plant Species of Gopalganj, Bihar (India)

Aleya Siddiquee ^1,*, Sarfaraz Ahmad ^2
1 Department of Botany, Jai Prakash University, India
² Head, Department of Botany, Jai Prakash University, India

ABSTRACT

In today's scenario, environment and lifestyle caused innumerable changes in human health. These changes are mostly negative in nature and have almost become irreversible; Diseases like cancer, diabetes, arthritis, rheumatoid arthritis, atherosclerosis and chronic inflammatory disorders have become very common. Taking into consideration the side effects and high cost of chemically synthesized agents, researchers are now turning towards traditional remedies and treatment. They turn out to be better medications with minimal side effects and less costs too. Therefore, some invasive alien species were selected which are common in Bihar region. These invading species have high biochemical activities, which help them spread and dominate in any regions. The purpose was to explore these biochemical activities of IAS (invasive alien species) to find better anti-inflammatory, anti-arthritic and antioxidant compounds from them. Five selected species were Ageratum conyzoides (L.) L, Eupatorium adenophorum Hort. Berol. ex Kunth, Galinsoga parviflora Cav. Mikania micrantha (L.) Willd. and Parthenium hysterophorus L. The extracts of the whole plant were tested on Cytotoxicity, anti-inflammatory, anti-arthritic and antioxidant activities. Eupatorium adenophorum Hort extract and Parthenium hysterophorus L. extract exhibit significant inhibitory action against Colon cell line (HT-29). Mikania micrantha (L.) extract was found to have highest antioxidant and anti-arthritic property with lowest IC50 of 32.23 µg/ml and 97.53 μg/ml respectively.

KEYWORDS
Antioxidant, Free Radical, Reactive Oxygen Species, Anti-arthritic, Anti-inflammatory, IC50, Invasive Alien Species

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Aleya Siddiquee , Sarfaraz Ahmad , "Cytotoxic and Antimicrobial Activity of Common Invasive Alien Plant Species of Gopalganj, Bihar (India)," Advances in Zoology and Botany, Vol. 10, No. 1, pp. 11 - 17, 2022. DOI: 10.13189/azb.2022.100102.

(b). APA Format:
Aleya Siddiquee , Sarfaraz Ahmad (2022). Cytotoxic and Antimicrobial Activity of Common Invasive Alien Plant Species of Gopalganj, Bihar (India). Advances in Zoology and Botany, 10(1), 11 - 17. DOI: 10.13189/azb.2022.100102.